Comprehensive Medicinal Chemistry II, Volume 7 : Therapeutic by David J Triggle, John B Taylor

By David J Triggle, John B Taylor

The 1st variation of complete Medicinal Chemistry used to be released in 1990 and was once rather well obtained. entire Medicinal Chemistry II is way greater than an easy updating of the contents of the 1st version. thoroughly revised and improved, this re-creation has been refocused to mirror the numerous advancements and adjustments during the last decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and extra. The content material includes the main updated, authoritative and accomplished reference textual content on modern medicinal chemistry and drug examine, overlaying significant healing sessions and pursuits, study approach and organization, high-throughput applied sciences, computer-assisted layout, ADME and chosen case histories. it's this insurance of the method, applied sciences, rules and functions of medicinal chemistry in one paintings that would make entire Medicinal Chemistry II a different paintings of reference and a unmarried element of access to the literature for pharmaceutical and biotechnology scientists of all disciplines and for lots of executives as well.Also on hand on-line through ScienceDirect (2006) - that includes broad searching, looking, and inner cross-referencing among articles within the paintings, plus dynamic linking to magazine articles and summary databases, making navigation versatile and straightforward. for additional info, pricing concepts and availability stopover at www.info.sciencedirect.com. * Comprehensively reports - the ideas, applied sciences, ideas and purposes of recent medicinal chemistry * presents an international and present standpoint of modern-day drug discovery strategy and discusses the foremost healing sessions and ambitions* features a designated selection of case reports and private assays reviewing the invention and improvement of key medicinal drugs

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Extra resources for Comprehensive Medicinal Chemistry II, Volume 7 : Therapeutic Areas II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology

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Gene 2000, 245, 223–235. 127. ; Gjertsen, B. ; Ernst, P. Stem Cells 2000, 18, 343–351. 128. Kinzler, K. ; Nilbert, M. ; Su, L. ; Bryan, T. ; Levy, D. ; Smith, K. ; Preisinger, A. ; McKechnie, D. Science 1991, 253, 661–665. 129. ; De Pol, A. Cell Prolif. 2000, 33, 1–18. 130. ; Taketo, M. M. Cancer Res. 1997, 57, 1644–1649. 131. ; Morin, P. ; Clevers, H. Adv. Cancer Res. 2000, 77, 1–24. 132. ; Peters, P. ; Clevers, H. Nat. Genet. 1998, 4, 379–383. 133. ; Iacobuzio-Donahue, C. ; Carter, M. ; Ko, M.

Maxwell, P. ; Wiesener, M. ; Chang, G. ; Clifford, S. ; Vaux, E. ; Cockman, M. ; Wykoff, C. ; Pugh, C. ; Maher, E. ; Ratcliffe, P. J. Nature 1999, 399, 271–275. Carroll, V. ; Ashcroft, M. Expert Rev. Mol. Med. 2005, 7, 1–16. Hicklin, D. ; Ellis, L. M. J. Clin. Oncol. 2005, 23, 1011–1027. ; Rusnati, M. Cytokine Growth Factor Rev. 2005, 16, 159–178. Yamaguchi, T. ; Rossant, J. Genes Dev. 1994, 8, 3032–3044. Lee, S. ; Schloss, D. ; Swain, J. L. J. Biol. Chem. 2000, 275, 33679–33687. ; Chang, H. ; Brady, J.

Lillard, J. W. Clin. Cancer Res. 2004, 10, 8743–8750. ; Cardones, A. ; Hwang, S. T. J. Dermatol. Sci. 2004, 36, 71–78. Schimanski, C. ; Berger, M. ; Galle, P. ; Moehler, M. Clin. Cancer Res. 2005, 11, 1743–1750. ; Gupta, P. ; Sgroi, D. ; Carey, V. ; Richardson, A. ; Weinberg, R. A. Cell 2005, 121, 335–348. Senger, D. ; Galli, S. ; Dvorak, A. ; Perruzzi, C. ; Harvey, V. ; Dvorak, H. F. Science 1983, 219, 983–985. ; Eberhardt, C. Nature 1996, 380, 435–439. Cancer Biology 238. 239. 240. 241. 242.

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