Commercializing nanomedicine : industrial applications, by Luca Escoffier, Mario Ganau, Julielynn Wong

By Luca Escoffier, Mario Ganau, Julielynn Wong

The nanotechnology is a fast-growing zone with a big power for novel purposes and unbelievable gains, however it is dealing with a tricky second due to the present turmoil and the doubts raised via these calling for a moratorium in examine actions so long as the doubtless opposed results of this self-discipline should not absolutely ascertained.

The booklet starts off with a radical creation to nanotechnology and nanomedicine and their investment resources. as soon as the contours of the subject material are pointed out, a scrutiny of the laws at present acceptable to nanotechnology and nanomedicine is performed including the exam of the highbrow estate rights that may be envisaged to guard and valorize the acknowledged concepts. using patents and different possible routes are thought of, including the present valuation tools, which exhibit how a quantitative valuation during this box isn't really a possibility. The examine duly considers the monetization of thoughts via usual and nonconventional options like advert hoc tasks, auctions, and brokerage.

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Several techniques from the field of nanotechnology are nowadays available for the miniaturization and biofunctionalization of diagnostic surfaces which can find a place in the screening armamentarium for molecular analyses. Indeed, many of them appear particularly suitable for high-sensitivity determination of panels of biomarkers. The main purpose of any technique for fabrication and biopatterning of surfaces is to create very small structures (at the micro- and nanometer scale) in a resist that can subsequently be transferred to the substrate material, often by etching.

Showed that CD133+ brain tumor cells can self-renew and undergo lineagespecific differentiation [78]. However, not only primary tumors are under the magnification lens: most death in fact occurs from metastases to distant organs than from their primary localization. Such metastases arise whenever tumor cells escape the primary microenvironment and spread via the bloodstream. The study of such blood-borne cancer cells, also known as circulating tumor cells (CTCs), offers a unique window into the neoplastic diffusion process.

Since DDI technologies and DNA nanoconstruction essentially depend on similar pre-requisites, which in particular are large and uniform hybridization efficiencies, combined with low nonspecific cross reactivity between individual sequences, this microarray approach has emerged along the past years as a promising tool for chip-based immunoassays meant to multiplex antigen detection. In fact, it is well known that the self-assembly of semisynthetic DNA–protein conjugates in so-called nanoassembled monolayers 02-Luca-Escoffier-02 July 24, 2015 18:13 PSP Book - 9in x 6in 02-Luca-Escoffier-02 In vitro Diagnostics (NAMs) makes it easy to generate unlimited reproducible, configurable nanoarrays exploiting precise and reliably protein/antibodie detection methods.

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