Chemistry of Heterocyclic Compounds: Isoquinolines, Part 3,

Isoquinolines Bearing uncomplicated aspect Chains (H. Schuster & F. Kathawala).

Isoquinolines and Their Hydrogenated Derivatives (O. Hoshino, et al.).

Index.Content:
Chapter I Isoquinolines Bearing uncomplicated facet Chains (pages 1–224): H. F. Schuster and F. Kathawala
Chapter II Isoquinolinols and Their Hydrogenated Derivatives (pages 225–543): Osamu Hoshino, Hiroshi Hart and Bunsuke Umezawa

Show description

Read or Download Chemistry of Heterocyclic Compounds: Isoquinolines, Part 3, Volume 38, Second Edition PDF

Best chemistry books

The Chemistry of Essential Oils and Artificial Perfumes - Volume 2 (Fourth Edition)

Quantity 2 (of the 2 quantity set): part titles are . .. (1) the fundamental Oil and Its smell . .. (2) parts of crucial Oils, artificial Perfumes and remoted Aromatics . .. (3) The research of crucial Oils.

Group 13 Chemistry I: Fundamental New Developments

During the last decade our view of chemistry has advanced considerably. while person researchers formerly inquisitive about particular parts of chemistry, equivalent to inorganic, natural, and so forth. we now take a extra holistic procedure. powerful and effective learn tasks now comprise no matter what points of the chemistry subdisciplines which are had to whole the meant paintings.

Extra info for Chemistry of Heterocyclic Compounds: Isoquinolines, Part 3, Volume 38, Second Edition

Example text

SUBSTITUTED 1-(3-AMINOETHYLAMINO)IsOQUINOLINES AND 3,4-DIHYDROISOQUINOLINES56 I H N-C H,CH 2-N. Type B = 3,4Dihydro Type A Type A o r B R A B H H /R' R' R' Formula cl 'HZ Et 1 FP ("C) 3 Cl,HZ,N, dihydrochloride 233 C. Isoquinolines Containing Arninophenyl Substituents Isoquinolines 78 as well as their reduced forms wherein the C1 basiccontaining substituent is a phenyl group bearing the amino functionality will be discussed in this section. Various useful applications as well as biological activities will be stressed.

Isoquinolines Having Basic-Containing Substituents at C1 35 TABLE 12. SUBSTITUTED ing l-{p-[2-(1-PYRROLIDINYL)ETHOX~ PHENY L}-1,2,3,4-TETRAHYDROISOQUINOLINES'B R'q R' 3 N-RZ , R3=p-C6H4-O-CHzCH2-N R' Formula R2 H CHZ--CHZ---C,H, H CH 2C H-C WH, CHZCH,C,H, OCH, CHLCH-C~HS I 6 CH' HS FP ("C) 81-113 C29H34N20 dih ydrochloride 91-145 C30H16N20 dihydrochloride 220-225 C30H16N20Z dihydrochloride I CH3 51-59 c 1 1H,,N2OZ dih ydrochloride TABLE 13. SUBSTITUTED 1-(3-AMINOETHYLAMINO)IsOQUINOLINES AND 3,4-DIHYDROISOQUINOLINES56 I H N-C H,CH 2-N.

19) 100 The acid-catalyzed reaction of anthranilonitrile(101)with 1-phenyl-2-methyl2-propanol(lO2) in xylene at 85 "Caffords 1-(2-aminophenyl)-3,3dimethyl-3,4. dihydrgisoquinoline (103), which can be catalytically reduced to -1We1 (Equation 20). bNHZ CN + 101 103 11. Isoquinolines Having Basic-Containing Substituents at C1 41 Bishop and Tuckers7 treated 1-(2-aminophenyl)-6,7-dimethoxy-3,4dihydroisoquinoline (105) with glyoxylic acid to produce the Schiff base 106. Subsequent reduction resulted in a cyclization to 107.

Download PDF sample

Rated 4.48 of 5 – based on 13 votes