Bioorganic Chemistry: Models and Applications by F.P. Schmidtchen

By F.P. Schmidtchen

Many organic platforms nonetheless carry various very fascinating molecular houses that to date can't be matched via manmade analogs. studying in regards to the rules and tips utilized by nature could provide entry to novel nanostructures, more advantageous catalysts for the functionalization of hydrocarbon compounds or might permit catalytic C-C bond formation below environmentally benign stipulations. This quantity recapitulates the state-of-the-art in these sectors of bioorganic chemistry that, instead of mimick the traditional instance, target to make use of the underlying ideas for important functions.

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5 Introduction .............................. Thiolate Coordinating Iron Porphyrins .............. P450 A n a l o g u e s with S u b s t r a t e R e c o g n i t i o n Sites . . . . E l e c t r o n Deficient M e t a l P o r p h y r i n s ............... Reductive O x y g e n Cleavage . . . . . . . . . . . 3 Final Comment . . . . . . . . . . . . . . . . 92 4 References . . . . . . . . . . . . . . . . . 93 Topics in Current Chemistry, Vol.

Voyer N, Maltais F (1993) Adv Mater 5:568 49. Voyer N, Gu6rin B (1992) J Chem Soc Chem Commun 1992:1253 50. Hibert MF, Hoflack S, Truwpp-Kallmeyer S, Bruinvels A (1993) M6decine/Sciences 9:31 51. LaBrenz SR, Kelly JW (1995) J Am Chem Soc 117:1655 52. Hille B (1984) Ionic Channels of Excitable Membranes, Sinauer, Sunderland, MA, USA 53. yoyer N, Robitaille M (1995) J Am Chem Soc 117:6599 and references cited therein 54. Akerfetdt KS, Lear JD, Wasserman ZR, Chung LA, DeGrado WF (1993) Ace Chem Res 26:191 55.

28). Although the compound exhibited a strong s-helical content in methanol, its conformation in a vesicle bilayer was different and undetermined. Nevertheless, irradiation of the Ru(II) complex of 74 resulted in a slow electron transfer. E. NI,]2 73 AO """, AO H ÷ 74 Cylinders = -L-S-L-Aib-L-S-L-S-L-(AQ)-L-S-L-L-S-L-Aib-L-S-LO < AQ = - I-IN-~COFig. 28. Schematic illustration of an artificial peptidic electron-transfer system designed to operate in a bilayer membrane. (Reproduced with the permission of Ref.

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