An Attempt to establish a pure scientific system of by Jöns Jakob Berzelius, John Black

By Jöns Jakob Berzelius, John Black

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These processes can be successfully employed in natural product synthesis176,178. The extensive work of Lubineau further demonstrated the merits of water with respect to the rates and selectivities of the Diels-Alder reaction. Since 1985 he has published a large number of articles dealing mainly with dienes that were rendered water soluble through the temporary introduction of a sugar moiety8,87f,153a,168,179. The efficiency of Diels-Alder reactions between these compounds and standard dienophiles is still significantly enhanced in aqueous solutions, despite the presence of the hydrophilic sugar group in the diene153a.

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